Paul Bissex has posted a great list of things not to do on your podcast:

• I Must Apologize for the Terrible Sound Quality of the Last Podcast
• I Must Apologize for the Terrible Sound Quality of the Present Podcast
• I Must Apologize for Not Making a Podcast in Several Days/Weeks/Months
• Thank You for All Your Emails Telling Me What I’m Doing Wrong
• I Need to Speak Very Quietly, My (Mom|Dad|Girlfriend|Ferret) is Sleeping
• There Is a Very Exciting Thing Coming at the End of This Podcast But I Won’t Tell You What It Is
• We Only Have One Microphone for the Three of Us
• We Are Laughing About This Thing, Ha Ha, You Kind of Had to Be There
• I Had Big Plans for This Episode But They Just Didn’t Work Out
• Please Listen to My Next Podcast, It Will Be Better Than This One I Promise

No one cares about any of that! Just do your best and be interesting. This is important because it is functionally impossible to skim a podcast as you can with text.